Ivo Jorge Prado Arnhold Selected Research

Combined Pituitary Hormone Deficiency

3/2022	Cushing disease due to a somatic USP8 mutation in a patient with evolving pituitary hormone deficiencies due to a germline GH1 splicing variant.
1/2021	Allelic Variants in Established Hypopituitarism Genes Expand Our Knowledge of the Phenotypic Spectrum.
1/2007	Hormonal, pituitary magnetic resonance, LHX4 and HESX1 evaluation in patients with hypopituitarism and ectopic posterior pituitary lobe.

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Ivo Jorge Prado Arnhold Research Topics

Disease

3	Pituitary Dwarfism 03/2022 - 01/2007
3	Combined Pituitary Hormone Deficiency 03/2022 - 01/2007
3	Precocious Puberty 07/2008 - 04/2006
2	Virilism (Virilization) 03/2018 - 04/2006
2	Primary Ovarian Insufficiency 01/2013 - 09/2006
2	Familial Testotoxicosis 07/2008 - 04/2006
2	Penis agenesis 09/2006 - 02/2005
2	Hypogonadism (Hypergonadotropic Hypogonadism) 09/2006 - 12/2005
1	Pituitary ACTH Hypersecretion 03/2022
1	Cushing Syndrome 03/2022
1	Neoplasms (Cancer) 03/2022
1	Weight Gain 03/2022
1	Diabetes Insipidus 01/2021
1	Holoprosencephaly (Arhinencephaly) 01/2021
1	Androgen-Insensitivity Syndrome (Testicular Feminization) 03/2018
1	Achalasia Addisonianism Alacrimia syndrome 01/2017
1	Alacrima 01/2017
1	Adrenal Insufficiency (Adrenal Gland Hypofunction) 01/2017
1	Esophageal Achalasia (Megaesophagus) 01/2017
1	Wounds and Injuries (Trauma) 01/2017
1	Cysts 01/2013
1	Cognitive Dysfunction 11/2011
1	Microcephaly 11/2011
1	Hypopituitarism (Sheehan's Syndrome) 01/2007
1	Gonadal Disorders 09/2006
1	46,XY Disorder of Sex Development (Male Pseudohermaphroditism) 09/2006

Drug/Important Bio-Agent (IBA)

4	Testosterone (Sustanon)FDA Link 03/2018 - 02/2005
3	Adrenocorticotropic Hormone (ACTH)FDA Link 03/2022 - 01/2007
3	LH Receptors (LH Receptor)IBA 07/2008 - 04/2006
2	FSH Receptors (FSH Receptor)IBA 01/2013 - 09/2006
2	Estradiol (Delestrogen)FDA LinkGeneric 01/2013 - 12/2005
2	EnzymesIBA 01/2007 - 12/2005
2	Luteinizing Hormone (Lutropin)FDA LinkGeneric 04/2006 - 12/2005
1	Hormones (Hormone)IBA 03/2022
1	Thyroid HormonesIBA 03/2022
1	Ubiquitin-Specific ProteasesIBA 03/2022
1	Dexamethasone (Maxidex)FDA LinkGeneric 03/2022
1	Hydrocortisone (Cortisol)FDA LinkGeneric 03/2022
1	Growth Hormone (Somatotropin)IBA 01/2021
1	Homeodomain Proteins (Proteins, Homeobox)IBA 01/2021
1	Acetylcysteine (Siran)FDA LinkGeneric 01/2017
1	AntioxidantsIBA 01/2017
1	Progesterone FDA LinkGeneric 01/2013
1	Insulin-Like Growth Factor I (IGF-1)IBA 11/2011
1	Cyproterone AcetateIBA 07/2008
1	Gonadotropin-Releasing Hormone (GnRH)FDA Link 07/2008
1	Ketoconazole (Nizoral)FDA LinkGeneric 07/2008
1	4-(fluoromethyl)phenyl phosphate (FMPP)IBA 07/2008
1	GonadotropinsIBA 07/2008
1	Gonadotropin ReceptorsIBA 09/2006
1	AndrogensIBA 04/2006
1	DNA (Deoxyribonucleic Acid)IBA 04/2006
1	beta Subunit Luteinizing HormoneIBA 12/2005
1	Human Follicle Stimulating HormoneIBA 12/2005

Therapy/Procedure

1	Castration 03/2018